Oncogenic and ligand-dependent activation of KIT/PDGFRA in surgical samples of imatinib-treated gastrointestinal stromal tumours (GISTs).
about
Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.Targeting Disease Persistence in Gastrointestinal Stromal TumorsPlatelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.The expression of KIT receptor dimers in gastrointestinal stromal tumors independent of c-kit mutation and SCF expression is associated with high-risk stratificationExpression of stem cell factor in gastrointestinal stromal tumors: Implications for proliferation and imatinib resistance.Investigational therapies up to Phase II which target PDGF receptors: potential anti-cancer therapeutics.Gene expression analysis predicts insect venom anaphylaxis in indolent systemic mastocytosis.Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-KitHigh CD133 expression levels in gastrointestinal stromal tumors.Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study.Platelet-derived growth factor receptor alpha expression improves the diagnostic assessment of gastrointestinal stromal tumours.
P2860
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P2860
Oncogenic and ligand-dependent activation of KIT/PDGFRA in surgical samples of imatinib-treated gastrointestinal stromal tumours (GISTs).
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Oncogenic and ligand-dependent ...... tinal stromal tumours (GISTs).
@en
Oncogenic and ligand-dependent ...... strointestinal stromal tumours
@nl
type
label
Oncogenic and ligand-dependent ...... tinal stromal tumours (GISTs).
@en
Oncogenic and ligand-dependent ...... strointestinal stromal tumours
@nl
prefLabel
Oncogenic and ligand-dependent ...... tinal stromal tumours (GISTs).
@en
Oncogenic and ligand-dependent ...... strointestinal stromal tumours
@nl
P50
P356
P1476
Oncogenic and ligand-dependent ...... stinal stromal tumours (GISTs)
@en
P2093
P304
P356
10.1002/PATH.2450
P50
P577
2009-01-01T00:00:00Z