Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames.
about
Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation.Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs.Fatty Acid-Modified Gapmer Antisense Oligonucleotide and Serum Albumin Constructs for Pharmacokinetic Modulation.Advances in the delivery of RNA therapeutics: from concept to clinical reality.The chemical evolution of oligonucleotide therapies of clinical utility.Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames.Physiological/pathological ramifications of transcription factors in the unfolded protein response.Molecular Mechanisms of Antisense Oligonucleotides.Antisense oligonucleotides targeting translation inhibitory elements in 5' UTRs can selectively increase protein levels.Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides.An RNA structure-mediated, posttranscriptional model of human α-1-antitrypsin expression.Antisense oligonucleotides: the next frontier for treatment of neurological disorders.Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs.Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts.Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines.Tapping the RNA world for therapeutics.RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus.
P2860
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P2860
Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh-hant
name
Translation efficiency of mRNA ...... upstream open reading frames.
@en
Translation efficiency of mRNA ...... upstream open reading frames.
@nl
type
label
Translation efficiency of mRNA ...... upstream open reading frames.
@en
Translation efficiency of mRNA ...... upstream open reading frames.
@nl
prefLabel
Translation efficiency of mRNA ...... upstream open reading frames.
@en
Translation efficiency of mRNA ...... upstream open reading frames.
@nl
P2093
P2860
P356
P1433
P1476
Translation efficiency of mRNA ...... upstream open reading frames.
@en
P2093
Michael T Migawa
Stanley T Crooke
Timothy A Vickers
Xue-Hai Liang
P2860
P2888
P304
P356
10.1038/NBT.3589
P577
2016-07-11T00:00:00Z
P6179
1009912947