Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients.
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Signaling Circuits and Regulation of Immune Suppression by Ovarian Tumor-Associated MacrophagesRole of immunotherapy for renal cell cancer in 2011Dendritic cell vaccination, immune regulation, and clinical outcomes in ovarian cancerTherapeutic cancer vaccines: past, present, and futurePD-1 as an emerging therapeutic target in renal cell carcinoma: current evidenceTargeted therapy in renal cell carcinoma: moving from molecular agents to specific immunotherapyWays to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytesControl of the immune response by pro-angiogenic factorsThe role of regulatory T cells in cancer immunologyRecent advances in therapeutic cancer vaccinesTargeting the tumor vasculature to enhance T cell activitySunitinib in the treatment of metastatic renal cell carcinomaMedical treatment of renal cancer: new horizonsSignal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapyMyeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacyImmunotherapeutic strategies for the treatment of renal cell carcinoma: where are we now?Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeuticsReduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors.Interface of signal transduction inhibition and immunotherapy in melanoma.Breaking through a plateau in renal cell carcinoma therapeutics: development and incorporation of biomarkersA phase I study of recombinant human interleukin-21 (rIL-21) in combination with sunitinib in patients with metastatic renal cell carcinoma (RCC).Phase 1 Dose-Escalation Study with LEC/chTNT-3 and Toceranib Phosphate (Palladia(®)) in Dogs with Spontaneous Malignancies.Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study.AACR centennial series: the biology of cancer metastasis: historical perspectiveThe immunocytokine NHS-IL12 as a potential cancer therapeuticNovel immunotherapy in metastatic renal cell carcinoma.Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression.Oncogene withdrawal engages the immune system to induce sustained cancer regression.Adjuvant therapy for renal cell carcinoma: past, present, and futureActivation of the human immune system by chemotherapeutic or targeted agents combined with the oncolytic parvovirus H-1.Targeting immune suppressing myeloid-derived suppressor cells in oncology.Development and application of 'phosphoflow' as a tool for immunomonitoringRenal cancer resistance to antiangiogenic therapy is delayed by restoration of angiostatic signaling.The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells.An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation.Immune consequences of decreasing tumor vasculature with antiangiogenic tyrosine kinase inhibitors in combination with therapeutic vaccines.Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects.Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.Higher frequencies of GARP(+)CTLA-4(+)Foxp3(+) T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T-cell functionality.Deciphering the anticancer mechanisms of sunitinib.
P2860
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P2860
Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@en
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@nl
type
label
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@en
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@nl
prefLabel
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@en
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@nl
P2093
P1476
Sunitinib reverses type-1 immu ...... renal cell carcinoma patients.
@en
P2093
Ali Golshayan
Amy Richmond
Brian Rini
James H Finke
Joanna Ireland
Jorge Garcia
Laura Wood
Patricia Rayman
Paul Elson
Robert Dreicer
P304
P356
10.1158/1078-0432.CCR-07-5212
P407
P577
2008-10-01T00:00:00Z