Calpain inhibitor MDL 28170 protects hypoxic-ischemic brain injury in neonatal rats by inhibition of both apoptosis and necrosis.
about
The effect of prenatal hypoxia on brain development: short- and long-term consequences demonstrated in rodent modelsEffects of a caspase and a calpain inhibitor on resting energy expenditures in normal and hypermetabolic rats: a pilot studyA pharmacological analysis of the neuroprotective efficacy of the brain- and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model.Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis.The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivationSulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen peroxide.Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins.Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain InjuryKnockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity.Neuroprotection against neonatal hypoxia/ischemia-induced cerebral cell death by prevention of calpain-mediated mGluR1alpha truncation.Enhancement of autophagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms.Neuroprotection in the newborn infantNeuronal cell death in neonatal hypoxia-ischemia.An updated patent review of calpain inhibitors (2012 - 2014).Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus.Oestrogen receptor subtype-specific repression of calpain expression and calpain enzymatic activity in neuronal cells--implications for neuroprotection against Ca-mediated excitotoxicity.Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain.Postnatal calpain inhibition elicits cerebellar cell death and motor dysfunction.Regulation of calpain activity in rat brain with altered Ca2+ homeostasis.
P2860
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P2860
Calpain inhibitor MDL 28170 protects hypoxic-ischemic brain injury in neonatal rats by inhibition of both apoptosis and necrosis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@en
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@nl
type
label
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@en
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@nl
prefLabel
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@en
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@nl
P2093
P1433
P1476
Calpain inhibitor MDL 28170 pr ...... f both apoptosis and necrosis.
@en
P2093
Akiko Ohmura
Akira Ishida
Goro Takada
Masanari Kawamura
Shinobu Miura
Wako Nakajima
P356
10.1016/J.BRAINRES.2004.12.050
P407
P577
2005-03-01T00:00:00Z