Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.

Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.

Item
http://www.wikidata.org/entity/Q46400015
Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway.Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.Statins improve survival by inhibiting spontaneous metastasis and tumor growth in a mouse melanoma model.A novel reporter system for molecular imaging and high-throughput screening of anticancer drugs.Statins are logical candidates for overcoming limitations of targeting therapies on malignancy: their potential application to gastrointestinal cancers.The DNA methyl transferase inhibitor, 5'-aza-2-deoxycitidine, enhances the apoptotic effect of Mevastatin in human leukemia HL-60 cells.Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts.Bisphosphonates and statins inhibit expression and secretion of MIP-1α via suppression of Ras/MEK/ERK/AML-1A and Ras/PI3K/Akt/AML-1A pathways.The role of ERK1/2 in 15-HETE-inhibited apoptosis in pulmonary arterial smooth muscle cells.Differences of statin activity in 2D and 3D pancreatic cancer cell cultures.Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.Differential roles of the mevalonate pathway in the development and survival of mouse Purkinje cells in culture.The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
P2860

Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.

Item
http://www.wikidata.org/entity/Q46400015
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
@zh-hant
name
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@en
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@nl
type
label
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@en
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@nl
prefLabel
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@en
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@nl
P1433
P1476
P2093
P2888
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
@en
P2093
P2888
P304
P31
P356
P433
P478
P577
P698
P921