Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
about
A self-sequestered calmodulin-like Ca²⁺ sensor of mitochondrial SCaMC carrier and its implication to Ca²⁺-dependent ATP-Mg/P(i) transportVisualizing functional motions of membrane transporters with molecular dynamics simulationsMitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searchingStructures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanismThe substrate specificity of mitochondrial carriers: mutagenesis revisitedA combination of receptor-based pharmacophore modeling & QM techniques for identification of human chymase inhibitorsP-loop conformation governed crizotinib resistance in G2032R-mutated ROS1 tyrosine kinase: clues from free energy landscapeTyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation.Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria.Interplay of Mg2+, ADP, and ATP in the cytosol and mitochondria: unravelling the role of Mg2+ in cell respiration.Tetrahydrofolate recognition by the mitochondrial folate transporter.Mapping conformational heterogeneity of mitochondrial nucleotide transporter in uninhibited states.3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors.Molecular Basis of MgATP Selectivity of the Mitochondrial SCaMC Carrier.Channel character of uncoupling protein-mediated transportMutation of the mitochondrial carrier SLC25A42 causes a novel form of mitochondrial myopathy in humansMolecular dynamics simulations of membrane channels and transportersHigh-chloride concentrations abolish the binding of adenine nucleotides in the mitochondrial ADP/ATP carrier family.Structure and function of mitochondrial carriers - role of the transmembrane helix P and G residues in the gating and transport mechanism.The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanismAtomistic modeling of alternating access of a mitochondrial ADP/ATP membrane transporter with molecular simulations.Mapping the nucleotide binding site of uncoupling protein 1 using atomic force microscopy.Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier.Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriersModelling the free energy profile of the mitochondrial ADP/ATP carrier.Single-nucleotide evolution quantifies the importance of each site along the structure of mitochondrial carriers.The substrate specificity of the human ADP/ATP carrier AAC1.Conformational dynamics of the mitochondrial ADP/ATP carrier: a simulation study.Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity.De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine.Computational studies of novel chymase inhibitors against cardiovascular and allergic diseases: mechanism and inhibition.Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.Ligand induced change of β2adrenergic receptor from active to inactive conformation and its implication for the closed/open state of the water channel: insight from molecular dynamics simulation, free energy calculation and Markov state model analysDynamics and interactions of AAC3 in DPC are not functionally relevant
P2860
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P2860
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@en
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@nl
type
label
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@en
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@nl
prefLabel
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@en
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@nl
P356
P1476
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
@en
P2093
Christophe Chipot
François Dehez
P304
12725-12733
P356
10.1021/JA8033087
P407
P577
2008-08-26T00:00:00Z