Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.
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Linoleic acid metabolite drives severe asthma by causing airway epithelial injuryDifferential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase proteinThe adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammationA distinctive alveolar macrophage activation state induced by cigarette smokingBeta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine modelThe epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammation in an asthma modelInducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaBSPDEF regulates goblet cell hyperplasia in the airway epitheliumIL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin productionAspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cellsAntigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free settingSTAT6 and PARP Family Members in the Development of T Cell-dependent Allergic InflammationStabilization of high-risk plaquesThe origin and role of innate lymphoid cells in the lungDendritic cells in lung immunopathologyEpithelial Sodium and Chloride Channels and AsthmaHost responses in tissue repair and fibrosisIL-4 and IL-13 signaling in allergic airway diseaseStrategic applications of gene expression: from drug discovery/development to bedsideThe cell biology of asthmaIL-13-induced airway mucus production is attenuated by MAPK13 inhibition.Using Periostin as a Biomarker in the Treatment of AsthmaGene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesisRole of infection in the development and exacerbation of asthmaSPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus productionDevelopment of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT61,8-Cineol Reduces Mucus-Production in a Novel Human Ex Vivo Model of Late RhinosinusitisThe role of CLCA proteins in inflammatory airway diseaseMultiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary InjuryMechanisms of fibrosis: therapeutic translation for fibrotic diseaseIL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroidsThe phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.B cell antigen presentation promotes Th2 responses and immunopathology during chronic allergic lung diseaseIL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis.Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/- mice.Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection.Somatic extracts of Marshallagia marshalli downregulate the Th2 associated immune responses in ovalbumin-induced airway inflammation in BALB/c mice.
P2860
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P2860
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Direct effects of interleukin- ...... ucus overproduction in asthma.
@en
Direct effects of interleukin- ...... ucus overproduction in asthma.
@nl
type
label
Direct effects of interleukin- ...... ucus overproduction in asthma.
@en
Direct effects of interleukin- ...... ucus overproduction in asthma.
@nl
prefLabel
Direct effects of interleukin- ...... ucus overproduction in asthma.
@en
Direct effects of interleukin- ...... ucus overproduction in asthma.
@nl
P2093
P356
P1433
P1476
Direct effects of interleukin- ...... ucus overproduction in asthma.
@en
P2093
David J Erle
Dean Sheppard
Douglas A Kuperman
Grace H Chang
Gregory M Dolganov
Jack A Elias
Laura L Koth
Xiaozhu Huang
P2888
P304
P356
10.1038/NM734
P407
P577
2002-07-01T00:00:00Z