Expression and efficient export of enzymatically active Mycobacterium tuberculosis glutamine synthetase in Mycobacterium smegmatis and evidence that the information for export is contained within the protein.
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Identification of two Mycobacterium tuberculosis H37Rv ORFs involved in resistance to killing by human macrophagesNon-classical protein secretion in bacteria.Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosisAll four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasisEvaluation of Mycobacterium tuberculosis genes involved in resistance to killing by human macrophagesGlutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigsIdentification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesisglnE is an essential gene in Mycobacterium tuberculosisTreatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication.High extracellular levels of Mycobacterium tuberculosis glutamine synthetase and superoxide dismutase in actively growing cultures are due to high expression and extracellular stability rather than to a protein-specific export mechanism.Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatisPart I: characterization of the extracellular proteome of the extreme thermophile Caldicellulosiruptor saccharolyticus by GeLC-MS2.Two-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins.Regulation of the Mycobacterium tuberculosis mce1 operon.The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis.The Mycobacterium tuberculosis complex-restricted gene cfp32 encodes an expressed protein that is detectable in tuberculosis patients and is positively correlated with pulmonary interleukin-10.Poly-L-glutamate/glutamine synthesis in the cell wall of Mycobacterium bovis is regulated in response to nitrogen availability.The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG.A new potential secretion pathway for recombinant proteins in Bacillus subtilis.An inhibitor of exported Mycobacterium tuberculosis glutamine synthetase selectively blocks the growth of pathogenic mycobacteria in axenic culture and in human monocytes: extracellular proteins as potential novel drug targets.Taxonomy, Physiology, and Natural Products of Actinobacteria.Multimer recognition and secretion by the non-classical secretion pathway in Bacillus subtilis.How are the non-classically secreted bacterial proteins released into the extracellular milieu?Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies.Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.Common Non-classically Secreted Bacterial Proteins with Experimental Evidence.Secretome analysis of diarrhea-inducing strains of Escherichia coliDifferential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform.Export of recombinant Mycobacterium tuberculosis superoxide dismutase is dependent upon both information in the protein and mycobacterial export machinery. A model for studying export of leaderless proteins by pathogenic mycobacteria.5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.Expression and purification of immunologically reactive DPPD, a recombinant Mycobacterium tuberculosis skin test antigen, using Mycobacterium smegmatis and Escherichia coli host cells.
P2860
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P2860
Expression and efficient export of enzymatically active Mycobacterium tuberculosis glutamine synthetase in Mycobacterium smegmatis and evidence that the information for export is contained within the protein.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Expression and efficient expor ...... contained within the protein.
@en
Expression and efficient expor ...... contained within the protein.
@nl
type
label
Expression and efficient expor ...... contained within the protein.
@en
Expression and efficient expor ...... contained within the protein.
@nl
prefLabel
Expression and efficient expor ...... contained within the protein.
@en
Expression and efficient expor ...... contained within the protein.
@nl
P2860
P356
P1476
Expression and efficient expor ...... contained within the protein.
@en
P2093
P2860
P304
22728-22735
P356
10.1074/JBC.272.36.22728
P407
P577
1997-09-01T00:00:00Z