The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.
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A systematic screen for protein-lipid interactions in Saccharomyces cerevisiaePhosphoinositide kinase signaling controls ER-PM cross-talk.A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling.A protein kinase network regulates the function of aminophospholipid flippases.Pkh-kinases control eisosome assembly and organization.The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover.The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.Communications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological AgingDown-regulating sphingolipid synthesis increases yeast lifespanExperimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in YeastSkn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae.Keeping sphingolipid levels nORMal.Uncoupling of mRNA synthesis and degradation impairs adaptation to host temperature in Cryptococcus neoformansMembranes in balance: mechanisms of sphingolipid homeostasis.Interruption of inositol sphingolipid synthesis triggers Stt4p-dependent protein kinase C signaling.Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function.Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast.Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.Distribution and functions of sterols and sphingolipids.Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.Target of rapamycin (TOR) in nutrient signaling and growth controlMechanisms regulating the protein kinases of Saccharomyces cerevisiae.Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availabilityPhospholipid flippases: building asymmetric membranes and transport vesicles.Analysis of cytochrome b(5) reductase-mediated metabolism in the phytopathogenic fungus Zymoseptoria tritici reveals novel functionalities implicated in virulence.Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathwaysCharacterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.Systems biology of AGC kinases in fungi.Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial functionRegulation of ceramide biosynthesis by TOR complex 2.Sphingolipids and lifespan regulation.Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.Roles for sphingolipids in Saccharomyces cerevisiae.Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy.Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae.Assessment of crosstalks between the Snf1 kinase complex and sphingolipid metabolism in S. cerevisiae via systems biology approaches.
P2860
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P2860
The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@en
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@nl
type
label
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@en
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@nl
prefLabel
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@en
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@nl
P2093
P2860
P356
P1476
The sphingoid long chain base ...... ncluding Ypk1, Ypk2, and Sch9.
@en
P2093
Robert C Dickson
Robert L Lester
Xiping Zhang
P2860
P304
22679-22687
P356
10.1074/JBC.M502972200
P407
P577
2005-04-19T00:00:00Z