A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.

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http://www.wikidata.org/entity/Q46449902
The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR ConformerInflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complexStructural allele-specific patterns adopted by epitopes in the MHC-I cleft and reconstruction of MHC:peptide complexes to cross-reactivity assessmentDistortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer PeptideCD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response.Immune system derived from homeostatic proliferation generates normal CD8 T-cell memory but altered repertoires and diminished heterologous immune responses.CrossTope: a curate repository of 3D structures of immunogenic peptide: MHC complexes.Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire.
P2860

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.

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http://www.wikidata.org/entity/Q46449902
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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name
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@en
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@nl
type
label
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@en
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@nl
prefLabel
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@en
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
A structural basis for CD8+ T ...... lar mimicry in autoreactivity.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698