Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment.
about
Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expressionAlterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2Dynamics of Hippocampal Protein Expression During Long-term Spatial Memory FormationX-linked focal epilepsy with reflex bathing seizures: Characterization of a distinct epileptic syndrome.Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's diseaseAssociation study of MiRSNPs with schizophrenia, tardive dyskinesia and cognition.Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteomeNonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions.Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent.Treadmill exercise after social isolation increases the levels of NGF, BDNF, and synapsin I to induce survival of neurons in the hippocampus, and improves depression-like behaviorSynapsin IIb as a functional marker of submissive behavior.Serotonin-mediated synapsin expression is necessary for long-term facilitation of the Aplysia sensorimotor synapse.H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depressionTemporal evolution of neurophysiological and behavioral features of synapsin I/II/III triple knock-out mice.Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticityDifferential regulation of synapsin phosphorylation by monocular deprivation in juveniles and adults.SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowthO-linked β-N-acetylglucosamine (O-GlcNAc) site thr-87 regulates synapsin I localization to synapses and size of the reserve pool of synaptic vesicles.Involvement of synaptic genes in the pathogenesis of autism spectrum disorders: the case of synapsinsIntrathecal immunoglobulin A and G antibodies to synapsin in a patient with limbic encephalitis.Specificity protein 1 (Sp1)-dependent activation of the synapsin I gene (SYN1) is modulated by RE1-silencing transcription factor (REST) and 5'-cytosine-phosphoguanine (CpG) methylation.The enhancement of stress-related memory by glucocorticoids depends on synapsin-Ia/IbSynapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels.Thiamine deficiency degrades the link between spatial behavior and hippocampal synapsin I and phosphorylated synapsin I protein levels.Autism-related behavioral abnormalities in synapsin knockout mice.Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse.Human Alzheimer's disease synaptic O-GlcNAc site mapping and iTRAQ expression proteomics with ion trap mass spectrometry.Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.Neuroprotective effect of biatractylenolide against memory impairment in D-galactose-induced aging mice.Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease.Compound IMM-H004, a novel coumarin derivative, protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia.Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice.
P2860
Q24301877-76A108AB-BCEF-481E-9EA5-D3296F850E3EQ28546579-908A913E-3AF5-4C13-860A-950C14430966Q30706228-E6B806E8-C6CB-4D27-823A-D6FCB6FF8462Q30975761-99AD8575-6834-405B-958C-E3A411865C8AQ33616828-4848C232-94BF-4712-8AF1-831D45542EB6Q33843010-348865E9-9F2B-4BB6-A8ED-017928121C87Q34441471-8F9B85EF-F514-4E0B-8429-5524CDB4B8F2Q34789789-5C1F80D8-849B-4373-9612-854C4C5B86EFQ35007780-C0A61216-349C-4A5E-AB1B-78941C494C90Q35041665-ECCD6BBF-4D4E-4ECE-9F14-160CDE71DC1BQ35583520-FA5AABA2-CAFB-43C4-80CE-FA09C582A015Q35635728-FA65C126-C46E-4BD7-BDB9-68596E2636D0Q36124985-33204404-8879-4B55-BF0D-A15F6C1485BBQ36588846-49053C18-B75B-4105-98D3-820EE8FDDF75Q36615008-74F2F266-27CA-4089-BDBD-711454C79C9CQ36839043-BF76108C-E8CD-485D-B434-4C4EFB7B3BC6Q37243982-19A5B70D-DC89-4E79-8134-AC47B807652BQ37380163-CCB9E118-C80A-4C70-BA22-08D26CDDF53CQ37563527-CE749366-93A9-4EEE-A65F-12651A0EDAEFQ38252584-9375C2BF-4690-4B91-8D8D-7880512EEB54Q38940806-95630910-D79B-4D2E-91B3-5BB43BF9E3F8Q39224229-6BF48C1D-560D-497A-9643-ABDC46BB6F3BQ41592132-A085949E-A220-4B05-945E-64B8F2406528Q41662474-5C2D7111-A587-4233-8156-39E345D3E223Q41807656-2400ED37-9E22-4489-A506-63AEA6A1BC0DQ41845734-81ECA75B-FC34-48E3-B82C-6E21E4361672Q43100218-BEE0FB0A-E50B-434F-9FC5-EEBB9B67C0BAQ44833697-E7A7DEAD-257E-48A9-B5CA-52B6748016FDQ46362244-5DA93614-E724-4769-8D13-42A6662A265EQ46845268-C256EA76-5B84-4E69-A25C-27906C0809BEQ47133791-B087BCB0-B77C-4532-8579-F8302EA8C269Q48369528-4BFA3C1E-6961-40DC-B95E-35993A34433DQ54945993-472F11C1-7461-42FF-9363-E2E308E4B5B8
P2860
Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@en
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@nl
type
label
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@en
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@nl
prefLabel
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@en
Synapsin-I- and synapsin-II-nu ...... ependent cognitive impairment.
@nl
P2093
P356
P1476
Synapsin-I- and synapsin-II-nu ...... dependent cognitive impairment
@en
P2093
Alessio Zanardi
Anna Corradi
Caterina Giacomini
Fabio Benfenati
Franco Onofri
P304
P356
10.1242/JCS.035063
P407
P577
2008-08-19T00:00:00Z