Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
about
Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitorsRejuvenating sirtuins: the rise of a new family of cancer drug targetsComparative modeling and benchmarking data sets for human histone deacetylases and sirtuin families.Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitorsIdentification and characterization of novel sirtuin inhibitor scaffoldsCharacterization of the anticancer effects of S115, a novel heteroaromatic thiosemicarbazone compound, in vitro and in vivo.Design of a novel nucleoside analog as potent inhibitor of the NAD dependent deacetylase, SIRT2Mechanisms and molecular probes of sirtuins.Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety.BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity.Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products.Resveratrol attenuates the release of inflammatory cytokines from human bronchial smooth muscle cells exposed to lipoteichoic acid in chronic obstructive pulmonary disease.Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding.Unsupervised pharmacophore modeling combined with QSAR analyses revealed novel low micromolar SIRT2 inhibitors.Stereoselective Synthesis, Synthetic and Pharmacological Application of Monoterpene-Based 1,2,4- and 1,3,4-Oxadiazoles.Computer- and Structure-Based Lead Identification for Epigenetic Targets
P2860
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P2860
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@en
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@nl
type
label
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@en
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@nl
prefLabel
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@en
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
@nl
P2093
P50
P356
P1476
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors
@en
P2093
Antero Salminen
Carsten Wittekindt
Elina Jarho
Jukka Leppänen
Tero Huhtiniemi
Tiina Suuronen
Valtteri M Rinne
P304
P356
10.1021/JM800639H
P407
P577
2008-07-22T00:00:00Z