P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia.
about
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptorThe Guanine-Based Purinergic System: The Tale of An Orphan NeuromodulationGPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors.The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repairForced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach.Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury.Cysteinyl leukotriene receptor 1 mediates LTD4-induced activation of mouse microglial cells in vitro.Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damageEstrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection.Astrocytic P2Y(1) receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia.The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrusATP as a multi-target danger signal in the brain.P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells.CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors.Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.Neurotransmitter signaling in the pathophysiology of microglia.Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases.Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cellsGuanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes.Critical Role of P2Y12 Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis.The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain
P2860
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P2860
P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@en
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@nl
type
label
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@en
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@nl
prefLabel
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@en
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@nl
P2093
P2860
P1476
P2Y1 and cysteinyl leukotriene ...... ary cultures of rat microglia.
@en
P2093
F Caciagli
I D'Alimonte
P Ballerini
P Di Iorio
P Patricelli
P2860
P304
P356
10.1177/039463200501800208
P577
2005-04-01T00:00:00Z