Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus.
about
Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infectionHsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism.Hyperthermia stimulates HIV-1 replicationTemperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes.Extracellular Hsp90 serves as a co-factor for NF-κB activation and cellular pathogenesis induced by an oncogenic herpesvirus.Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV.Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance.The co-chaperone BAG3 regulates Herpes Simplex Virus replication.Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cellsInhibition of HSP90 attenuates porcine reproductive and respiratory syndrome virus production in vitroRegulation of Viral Replication, Apoptosis and Pro-Inflammatory Responses by 17-AAG during Chikungunya Virus Infection in Macrophages.Viral interaction with molecular chaperones: role in regulating viral infection.Broad action of Hsp90 as a host chaperone required for viral replication.Hsp90 inhibitor reduces porcine circovirus 2 replication in the porcine monocytic line 3D4/31.HSP90: a promising broad-spectrum antiviral drug target.17-allylamino-17-(demethoxy)geldanamycin (17-AAG) is a potent and effective inhibitor of human cytomegalovirus replication in primary fibroblast cells.Geldanamycin, a ligand of heat shock protein 90, inhibits herpes simplex virus type 2 replication both in vitro and in vivo.
P2860
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P2860
Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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name
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@en
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@nl
type
label
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@en
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@nl
prefLabel
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@en
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@nl
P2093
P2860
P1476
Geldanamycin, a potent and spe ...... tion of human cytomegalovirus.
@en
P2093
Hiromi Imazu
Junji Tanaka
Kouhei Uechi
Miho Uhara
Ryoko Kitagawa
Walid Basha
P2860
P304
P356
10.1177/095632020501600206
P577
2005-01-01T00:00:00Z