Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds.
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Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled CompoundsPhysiological parameters for oral delivery and in vitro testingRhamnogalacturonan-I Based Microcapsules for Targeted Drug ReleaseModes of Disintegration of Solid Foods in Simulated Gastric Environment.The use of biorelevant dissolution media to forecast the in vivo performance of a drug.Disintegration of solid foods in human stomach.Preserving viability of Lactobacillus rhamnosus GG in vitro and in vivo by a new encapsulation system.Predictive models for oral drug absorption: from in silico methods to integrated dynamical models.FDA critical path initiatives: opportunities for generic drug development.pH-Dependent Solubility and Dissolution Behavior of Carvedilol--Case Example of a Weakly Basic BCS Class II Drug.Effect of Gastric Fluid Volume on the In Vitro Dissolution and In Vivo Absorption of BCS Class II Drugs: a Case Study with NifedipineCharacterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies.Biorelevant in-vitro performance testing of orally administered dosage forms.Dissolution testing of oral modified-release dosage forms.Coupling biorelevant dissolution methods with physiologically based pharmacokinetic modelling to forecast in-vivo performance of solid oral dosage forms.Pros and cons of methods used for the prediction of oral drug absorption.Drug release from matrix tablets: physiological parameters and the effect of food.Solution-mediated phase transformation of haloperidol mesylate in the presence of sodium lauryl sulfate.Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions.Oral uptake of nanoparticles: human relevance and the role of in vitro systems.Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement.pH-triggered drug release from biodegradable microwells for oral drug delivery.The electrochemical behavior of nitinol in simulated gastric fluid.In-vitro evaluation of performance of solid immediate release dosage forms of weak bases in upper gastrointestinal lumen: experience with miconazole and clopidogrel salts.SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization.The Biopharmaceutics Classification System: subclasses for in vivo predictive dissolution (IPD) methodology and IVIVCComparison of dissolution profiles for sustained release resinates of BCS class I drugs using USP apparatus 2 and 4: a technical note.A Mixed Micelle Formulation for Oral Delivery of Vitamin KSimulated food effects on drug release from ethylcellulose: PVA-PEG graft copolymer-coated pellets.Measurement of drug concentration in the stomach after intragastric administration of drug solution to healthy volunteers: analysis of intragastric fluid dynamics and drug absorption.Establishment of in vitro-in vivo equivalence of highly variable drugs - a generic product development perspective.Stability of oleuropein in the human proximal gut.Identification of key factors affecting the oral absorption of salts of lipophilic weak acids: a case example.Comparative survival of commercial probiotic formulations: tests in biorelevant gastric fluids and real-time measurements using microcalorimetry.Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo.Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC-MS/MS for application to a pharmacokinetic study in rats.Assessing the risk of alcohol-induced dose dumping from sustained-release oral dosage forms: in vitro-in silico approach.Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility.Mesoporous silica-based dosage forms improve release characteristics of poorly soluble drugs: case example fenofibrate.Feasibility of capsule endoscopy for direct imaging of drug delivery systems in the fasted upper-gastrointestinal tract.
P2860
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P2860
Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Simulation of fasting gastric ...... ution of lipophilic compounds.
@en
Simulation of fasting gastric ...... ution of lipophilic compounds.
@nl
type
label
Simulation of fasting gastric ...... ution of lipophilic compounds.
@en
Simulation of fasting gastric ...... ution of lipophilic compounds.
@nl
prefLabel
Simulation of fasting gastric ...... ution of lipophilic compounds.
@en
Simulation of fasting gastric ...... ution of lipophilic compounds.
@nl
P2093
P1476
Simulation of fasting gastric ...... ution of lipophilic compounds.
@en
P2093
Christos Reppas
James Butler
Jennifer Dressman
John Hempenstall
Maria Vertzoni
P304
P356
10.1016/J.EJPB.2005.03.002
P407
P577
2005-08-01T00:00:00Z