about
Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.Fluorescent natural products as probes and tracers in biology.Semisynthesis and biological activity of aminoacyl triesters of squamocin, an annonaceous acetogenin.Synthesis of 6-amino-5-cyano-1,4-disubstituted-2(1H)-pyrimidinones via copper-(I)-catalyzed alkyne-azide 'click chemistry' and their reactivity.Indium-labeled macrocyclic conjugates of naltrindole: high-affinity radioligands for in vivo studies of peripheral delta opioid receptors.Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: synthesis and covalent binding studies.Remarkable substituent effect: beta-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III.Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter.Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probeRapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening
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description
hulumtues
@sq
researcher
@en
wetenschapper
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հետազոտող
@hy
name
Romain A Duval
@ast
Romain A Duval
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Romain A Duval
@es
Romain A Duval
@nl
Romain A Duval
@sl
type
label
Romain A Duval
@ast
Romain A Duval
@en
Romain A Duval
@es
Romain A Duval
@nl
Romain A Duval
@sl
prefLabel
Romain A Duval
@ast
Romain A Duval
@en
Romain A Duval
@es
Romain A Duval
@nl
Romain A Duval
@sl
P108
P106
P108
P21
P31
P496
0000-0002-0125-506X