Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice.
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Therapeutic targets in the ASK1-dependent stress signaling pathwaysTrophic factors as modulators of motor neuron physiology and survival: implications for ALS therapyUbiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells.ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity.CIIA prevents SOD1(G93A)-induced cytotoxicity by blocking ASK1-mediated signalingLoss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse developmentOpposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.A fruitful endeavor: modeling ALS in the fruit flyDeath Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis.Roles of vitamin D in amyotrophic lateral sclerosis: possible genetic and cellular signaling mechanisms.Impact of opiate-HIV-1 interactions on neurotoxic signaling.Targeting ASK1 in ER stress-related neurodegenerative diseases.Glaucoma: an extension of various chronic neurodegenerative disorders.ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.The role of endoplasmic reticulum stress in neurodegenerative disease.Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?FPipTB, a benzimidazole derivative, induces chondrosarcoma cell apoptosis via endoplasmic reticulum stress and apoptosis signal-regulating kinase 1.Retinoschisin is linked to retinal Na/K-ATPase signaling and localizationVEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK.The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.
P2860
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P2860
Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Activation of the stress-activ ...... sclerosis in transgenic mice.
@en
Activation of the stress-activ ...... sclerosis in transgenic mice.
@nl
type
label
Activation of the stress-activ ...... sclerosis in transgenic mice.
@en
Activation of the stress-activ ...... sclerosis in transgenic mice.
@nl
prefLabel
Activation of the stress-activ ...... sclerosis in transgenic mice.
@en
Activation of the stress-activ ...... sclerosis in transgenic mice.
@nl
P2093
P1433
P1476
Activation of the stress-activ ...... sclerosis in transgenic mice.
@en
P2093
Carolina Montano
Dawn M Gregor
Geoffry L Curran
Joseph F Poduslo
Karunya K Kandimalla
Silvina S Holasek
Thomas M Wengenack
P304
P356
10.1016/J.BRAINRES.2005.03.037
P407
P577
2005-04-25T00:00:00Z