Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
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Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndromeBarrier requirements as the evolutionary "driver" of epidermal pigmentation in humansProtease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitisMolecular Genetic of Atopic dermatitis: An UpdateSkin Physiology of the Neonate and Infant: Clinical ImplicationsSpecificity profiling of seven human tissue kallikreins reveals individual subsite preferencesCandidate single nucleotide polymorphism markers for arsenic responsiveness of protein targetsEvidence that stress to the epidermal barrier influenced the development of pigmentation in humansDecreased cutaneous resonance running time in cured leprosy subjectsMurine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators.Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptensDirect visualization of lipid domains in human skin stratum corneum's lipid membranes: effect of pH and temperature.Improving diaper design to address incontinence associated dermatitis.Infant skin-cleansing product versus water: a pilot randomized, assessor-blinded controlled trial.Epidermal permeability barrier recovery is delayed in vitiligo-involved sitesThe extended cleavage specificity of human thrombin.Abnormal epidermal barrier recovery in uninvolved skin supports the notion of an epidermal pathogenesis of psoriasisIncreased expression of cathelicidin by direct activation of protease-activated receptor 2: possible implications on the pathogenesis of rosacea.Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis.Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and functionThe clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin.Cholinergic induction of perspiration attenuates nonhistaminergic pruritus in the skin of patients with atopic dermatitis and healthy controls.Topical hesperidin prevents glucocorticoid-induced abnormalities in epidermal barrier function in murine skin.Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.Protease-Activated Receptor-2 Is Associated with Terminal Differentiation of Epidermis and Eccrine Sweat Glands.Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification?sPLA2 and the epidermal barrier.Do early skin care practices alter the risk of atopic dermatitis? A case-control study.The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasiaCellular changes that accompany shedding of human corneocytes.Interactions among stratum corneum defensive functions.Second cite.Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patientsEpidermal sphingolipids: metabolism, function, and roles in skin disorders.Skin hydration: a review on its molecular mechanisms.Biological lipid membranes for on-demand, wireless drug delivery from thin, bioresorbable electronic implantsHeavy Cigarette Smokers in a Chinese Population Display a Compromised Permeability BarrierCharacterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.Skin irritation and sensitization: mechanisms and new approaches for risk assessment. 1. Skin irritation.pH-regulated mechanisms account for pigment-type differences in epidermal barrier function
P2860
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P2860
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Sustained serine proteases act ...... and stratum corneum integrity.
@en
Sustained serine proteases act ...... and stratum corneum integrity.
@nl
type
label
Sustained serine proteases act ...... and stratum corneum integrity.
@en
Sustained serine proteases act ...... and stratum corneum integrity.
@nl
prefLabel
Sustained serine proteases act ...... and stratum corneum integrity.
@en
Sustained serine proteases act ...... and stratum corneum integrity.
@nl
P2093
P1476
Sustained serine proteases act ...... and stratum corneum integrity.
@en
P2093
Barbara E Brown
Debra Crumrine
Diane Roseeuw
Jean-Pierre Hachem
Kenneth R Feingold
Mao-Quiang Man
Peter M Elias
Vera Rogiers
Yoshikazu Uchida
P304
P356
10.1111/J.0022-202X.2005.23838.X
P407
P577
2005-09-01T00:00:00Z
P6179
1003562149