Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.
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KymographClear and KymographDirect: two tools for the automated quantitative analysis of molecular and cellular dynamics using kymographs.Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans ciliaCentriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans.IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans.Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3ACUnexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins.The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gateCilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes.Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements.Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes.Why motor proteins team up - Intraflagellar transport in C. elegans cilia.The Intraflagellar Transport Machinery.Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.High-resolution real-time dual-view imaging with multiple point of view microscopy.A motor relay on ciliary tracks.Dynamics of the IFT machinery at the ciliary tip.Single-Molecule Fluorescence Microscopy in Living Caenorhabditis elegans.Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.Trainspotting in a cilium.Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B.Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.The Microtubule-Associated Protein Tau Mediates the Organization of Microtubules and Their Dynamic Exploration of Actin-Rich Lamellipodia and Filopodia of Cortical Growth Cones.Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons.Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia.Cilia length and intraflagellar transport regulation by kinases PKG-1 and GCK-2 in C. elegans sensory neurons.The axonal transport motor kinesin-2 navigates microtubule obstacles via protofilament switching.Human profilin 1 is a negative regulator of CTL mediated cell-killing and migration.Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.Cell-Specific α-Tubulin Isotype Regulates Ciliary Microtubule Ultrastructure, Intraflagellar Transport, and Extracellular Vesicle Biology.Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway.Reconstitution reveals motor activation for intraflagellar transport
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P2860
Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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@zh-hans
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name
Functional differentiation of ...... transport in C. elegans cilia.
@en
Functional differentiation of ...... transport in C. elegans cilia.
@nl
type
label
Functional differentiation of ...... transport in C. elegans cilia.
@en
Functional differentiation of ...... transport in C. elegans cilia.
@nl
prefLabel
Functional differentiation of ...... transport in C. elegans cilia.
@en
Functional differentiation of ...... transport in C. elegans cilia.
@nl
P2093
P2860
P356
P1433
P1476
Functional differentiation of ...... transport in C. elegans cilia.
@en
P2093
Felix Oswald
Jonathan M Scholey
Pierre Mangeol
P2860
P2888
P304
P356
10.1038/NCB3263
P577
2015-11-02T00:00:00Z