about
Guidelines for the use and interpretation of assays for monitoring autophagyAntimitotic drugs in the treatment of cancerIn vitro effects of 2-methoxyestradiol on morphology, cell cycle progression, cell death and gene expression changes in the tumorigenic MCF-7 breast epithelial cell line.An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot studyChemical analyses of Ukrain, a semi-synthetic Chelidonium majus alkaloid derivative, fail to confirm its trimeric structure.Effects of ω3- and ω6-polyunsaturated fatty acids on RANKL-induced osteoclast differentiation of RAW264.7 cells: a comparative in vitro study.Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case studyUkrain(TM), a semisynthetic Chelidonium majus alkaloid derivative, acts by inhibition of tubulin polymerization in normal and malignant cell lines.Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.Novel estradiol analogue induces apoptosis and autophagy in esophageal carcinoma cells.Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays.A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell linesInduction of the intrinsic apoptotic pathway via a new antimitotic agent in an esophageal carcinoma cell lineIn vitro effects of 2-methoxyestradiol-bis-sulphamate on reactive oxygen species and possible apoptosis induction in a breast adenocarcinoma cell line.Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines.A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis.Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic Plasmodium falciparum parasitesEx vivo apoptotic and autophagic influence of an estradiol analogue on platelets.Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells.Piperine alleviates osteoclast formation through the p38/c-Fos/NFATc1 signaling axis.Synergistic anticancer potential of dichloroacetate and estradiol analogue exerting their effect via ROS-JNK-Bcl-2-mediated signalling pathways.Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.17-beta-estradiol analog inhibits cell proliferation by induction of apoptosis in breast cell lines.In vitro changes in mitochondrial potential, aggresome formation and caspase activity by a novel 17-β-estradiol analogue in breast adenocarcinoma cells.Sulphamoylated estradiol analogue induces antiproliferative activity and apoptosis in breast cell lines.2-Methoxyestradiol-bis-sulphamate refrains from inducing apoptosis and autophagy in a non-tumorigenic breast cell lineThe in vitro effects of 2-methoxyestradiol-bis-sulphamate on cell numbers, membrane integrity and cell morphology, and the possible induction of apoptosis and autophagy in a non-tumorigenic breast epithelial cell line.In vitro effects of 2-methoxyestradiol-bis-sulphamate on the non-tumorigenic MCF-12A cell line.In vitro effects of Sutherlandia frutescens water extracts on cell numbers, morphology, cell cycle progression and cell death in a tumorigenic and a non-tumorigenic epithelial breast cell line.In vitro effects of 2-methoxyestradiol on cell numbers, morphology, cell cycle progression, and apoptosis induction in oesophageal carcinoma cells.In vitro effects of 2-methoxyestradiol on cell morphology and Cdc2 kinase activity in SNO oesophageal carcinoma cells.Influence of 2-methoxyestradiol on cell morphology and cdc2 kinase activity in WHCO3 esophageal carcinoma cells.Ex vivo Determination of an Estradiol Analogue-Induced Changes on Platelet Morphology and Angiogenic Biomarkers.An overview of the role of platelets in angiogenesis, apoptosis and autophagy in chronic myeloid leukaemia.Effects of arachidonic acid, docosahexaenoic acid and prostaglandin E(2) on cell proliferation and morphology of MG-63 and MC3T3-E1 osteoblast-like cells.The effects of prostaglandin A2 on cell growth, cell cycle status and apoptosis induction in HeLa and MCF-7 cells.In vitro effects of an in silico-modelled 17β-estradiol derivative in combination with dichloroacetic acid on MCF-7 and MCF-12A cells.Isolation and characterization of an anticoagulant present in the salivary glands of the bont-legged tick, Hyalomma truncatum.Bax/Bcl-2 expression levels of 2-methoxyestradiol-exposed esophageal cancer cells.Tumor cell culture survival following glucose and glutamine deprivation at typical physiological concentrations.
P50
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P50
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հետազոտող
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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Annie Joubert
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0000-0002-6931-7554
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lccn-n2017066221