Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments.
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Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin.Monitoring the direct and indirect damage of DNA bases and polynucleotides by using time-resolved infrared spectroscopyOxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesionsIntrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU).Spirodi(iminohydantoin) products from oxidation of 2'-deoxyguanosine in the presence of NH4Cl in nucleoside and oligodeoxynucleotide contexts.Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxideMechanistic aspects of hydration of guanine radical cations in DNA.Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions.Structural, energetic and dynamic properties of guanine(C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair.Oxidation of guanine by carbonate radicals derived from photolysis of carbonatotetramminecobalt(III) complexes and the pH dependence of intrastrand DNA cross-links mediated by guanine radical reactions.Solvent exposure associated with single abasic sites alters the base sequence dependence of oxidation of guanine in DNA in GG sequence contextsFree radical biology and medicine: it's a gas, man!Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosinespH-Dependent Equilibrium between 5-Guanidinohydantoin and Iminoallantoin Affects Nucleotide Insertion Opposite the DNA Lesion.Guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin induces mutations when bypassed by DNA polymerases and is a substrate for base excision repair.Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosineMethylation of 2'-deoxyguanosine by a free radical mechanism.Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair.Formation and processing of DNA damage substrates for the hNEIL enzymes.Rates of chemical cleavage of DNA and RNA oligomers containing guanine oxidation products.Formation and repair of oxidatively generated damage in cellular DNA.Synthesis and characterization of the oxidized dGTP lesions spiroiminodihydantoin-2'-deoxynucleoside-5'- triphosphate and guanidinohydantoin-2'-deoxynucleoside-5'- triphosphate.G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA.Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairingComputational studies of electronic circular dichroism spectra predict absolute configuration assignments for the guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin.8-Oxo-7,8-dihydro-2'-deoxyguanosine and abasic site tandem lesions are oxidation prone yielding hydantoin products that strongly destabilize duplex DNA.Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch.
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P2860
Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments.
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2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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name
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@en
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@nl
type
label
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@en
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@nl
prefLabel
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@en
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@nl
P2093
P356
P1476
Oxidation of guanine and 8-oxo ...... xygen-18 labeling experiments.
@en
P2093
Conor Crean
Nicholas E Geacintov
Vladimir Shafirovich
P304
P356
10.1002/ANIE.200500991
P407
P577
2005-08-01T00:00:00Z