Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation.
about
Expression and alternative splicing of the cytochrome P-450 CYP2A7Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3AInvolvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadineIn vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide)Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomesIn vitro cytochrome P450-mediated hepatic activities for five substrates in specific pathogen free chickens.Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP.Organotypic liver culture models: meeting current challenges in toxicity testing.The Relation between Hepatotoxicity and the Total Coumarin Intake from Traditional Japanese Medicines Containing Cinnamon Bark.Genetics of tobacco use.Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro.Potent and non-specific inhibition of cytochrome P450 by JM216, a new oral platinum agent.Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array.Generation of hepatocytes expressing functional cytochromes P450 from a pancreatic progenitor cell line in vitro.In vitro assessment of human cytochrome P450.Synthesis, radiolabelling and in vitro and in vivo evaluation of a novel fluorinated ABP688 derivative for the PET imaging of metabotropic glutamate receptor subtype 5.The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipelineCytochrome p450 assays.A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin.Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.Genetics of Tobacco Use.An In Silico Method for Screening Nicotine Derivatives as Cytochrome P450 2A6 Selective Inhibitors Based on Kernel Partial Least Squares.Species variation in the enantioselective metabolism of tegafur to 5-fluorouracil among rats, dogs and monkeys.Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to CoumarinLiver 'organ on a chip'.Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A.Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms.Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase.Effect of buffer conditions on CYP2C8-mediated paclitaxel 6α-hydroxylation and CYP3A4-mediated triazolam α- and 4-hydroxylation by human liver microsomes.Species and sex differences of testosterone and nifedipine oxidation in liver microsomes of rat, dog and monkey.Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates.Characterization of feline cytochrome P450 2B6.Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.
P2860
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P2860
Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Species differences and interi ...... l, and testosterone oxidation.
@en
Species differences and interi ...... l, and testosterone oxidation.
@nl
type
label
Species differences and interi ...... l, and testosterone oxidation.
@en
Species differences and interi ...... l, and testosterone oxidation.
@nl
prefLabel
Species differences and interi ...... l, and testosterone oxidation.
@en
Species differences and interi ...... l, and testosterone oxidation.
@nl
P2093
P1476
Species differences and interi ...... l, and testosterone oxidation.
@en
P2093
P304
P356
10.1016/0003-9861(92)90115-D
P407
P577
1992-10-01T00:00:00Z