The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
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Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal InfectionExtracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue.Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.A comparison of pneumolysin activity and concentration in vitro and in vivo in a rabbit endophthalmitis model.Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.
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The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
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2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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name
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@en
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@nl
type
label
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@en
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@nl
prefLabel
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@en
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@nl
P2093
P2860
P1476
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
@en
P2093
Aziz Hafidi
Didier Dulon
Graeme Cowan
Liam Skinner
Maryline Beurg
Yannick Hondarrague
P2860
P304
P356
10.1113/JPHYSIOL.2005.092478
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P577
2005-07-28T00:00:00Z