Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease.
about
Comparison of peptide array substrate phosphorylation of c-Raf and mitogen activated protein kinase kinase kinase 8Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microgliaGut hormones: emerging role in immune activation and inflammation.The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase.Central activation of the cholinergic anti-inflammatory pathway reduces surgical inflammation in experimental post-operative ileusThe Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation.Biological therapy in the management of recent-onset Crohn's disease: why, when and how?Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications.Biologics in Crohn's disease: searching indicators for outcome.New therapeutic strategies for treatment of inflammatory bowel disease.Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa.The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's diseaseMitogen activated protein kinases: a role in inflammatory bowel disease?Kinome profiling.Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96.Epithelial: lamina propria lymphocyte interactions promote epithelial cell differentiation.New furin inhibitors based on weakly basic amidinohydrazones.Acute stress elicited by bungee jumping suppresses human innate immunityGITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice.Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.Inflammatory genes are novel prognostic biomarkers for colorectal cancer.Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease.The novel orally active guanylhydrazone CPSI-2364 prevents postoperative ileus in mice independently of anti-inflammatory vagus nerve signaling.
P2860
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P2860
Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@en
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@nl
type
label
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@en
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@nl
prefLabel
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@en
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@nl
P2093
P1476
Specific inhibition of c-Raf a ...... ion in severe Crohn's disease.
@en
P2093
Auke Verhaar
Bernt van den Blink
Daniel Hommes
Fibo ten Kate
Mark Löwenberg
Sander van Deventer
P304
P356
10.4049/JIMMUNOL.175.4.2293
P407
P577
2005-08-01T00:00:00Z