Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
about
Fuzziness: linking regulation to protein dynamicsModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseDevelopmental Dynamics of Rett SyndromeMECP2 disorders: from the clinic to mice and backA review of Rett syndrome (RTT) with induced pluripotent stem cellsEpigenetic mechanisms in diurnal cycles of metabolism and neurodevelopmentAnalysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivoOver-expression of either MECP2_e1 or MECP2_e2 in neuronally differentiated cells results in different patterns of gene expressionMecp2-null mice provide new neuronal targets for Rett syndrome.MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapyExperimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin DamageRecent advances in MeCP2 structure and function.MeCP2 binds cooperatively to its substrate and competes with histone H1 for chromatin binding sitesNovel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes.Experimental models of Rett syndrome based on Mecp2 dysfunction.miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.Complexities of Rett syndrome and MeCP2Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements.Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenesMECP2, a gene associated with Rett syndrome in humans, shows conserved coding regions, independent Alu insertions, and a novel transcript across primate evolutionLinking epigenetics to human disease and Rett syndrome: the emerging novel and challenging concepts in MeCP2 research.Cerebellar associative sensory learning defects in five mouse autism models.Methyl CpG-binding protein isoform MeCP2_e2 is dispensable for Rett syndrome phenotypes but essential for embryo viability and placenta development.Rett syndrome: genes, synapses, circuits, and therapeuticsALS mutations in TLS/FUS disrupt target gene expression.Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression.Regulatory functions and pathological relevance of the MECP2 3'UTR in the central nervous system.MECP2 genomic structure and function: insights from ENCODERett syndrome: recent research progress.Epigenetics, autism spectrum, and neurodevelopmental disorders.Breathing challenges in Rett syndrome: lessons learned from humans and animal models.Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.MeCP2: structure and function.Rett syndrome and MeCP2.MeCP2: multifaceted roles in gene regulation and neural development.Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS).MECP2, a multi-talented modulator of chromatin architecture.Comparative analysis of linker histone H1, MeCP2, and HMGD1 on nucleosome stability and target site accessibility.Isoform-specific anti-MeCP2 antibodies confirm that expression of the e1 isoform strongly predominates in the brain.
P2860
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P2860
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@en
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@nl
type
label
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@en
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@nl
prefLabel
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@en
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@nl
P2093
P2860
P356
P1476
Differential distribution of the MeCP2 splice variants in the postnatal mouse brain.
@en
P2093
Arthur P Arnold
N Carolyn Schanen
Yong-Hwan Kim
P2860
P304
P356
10.1002/CNE.21264
P407
P577
2007-04-01T00:00:00Z