PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor.
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The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotectionThe 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migrationBinding of NIR-conPK and NIR-6T to astrocytomas and microglial cells: evidence for a protein related to TSPO.Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemiaPK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO).Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.The translocator protein (TSPO) ligand PK11195 induces apoptosis and cell cycle arrest and sensitizes to chemotherapy treatment in pre- and post-relapse neuroblastoma cell lines.The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor.Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides.Expression and modulation of translocator protein and its partners by hypoxia reoxygenation or ischemia and reperfusion in porcine renal models.Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.The translocator protein as a potential molecular target for improved treatment efficacy in photodynamic therapy.Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell LinesRasagiline prevents apoptosis induced by PK11195, a ligand of the outer membrane translocator protein (18 kDa), in SH-SY5Y cells through suppression of cytochrome c release from mitochondria.A translocator protein ligand PK11195 shows antigrowth activity in human choriocarcinoma cells.Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195.Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-alpha-induced cell death in MCF-7 cellsMetabolism: Drug discovery goes for a swim.Potential involvement of the 18 kDa translocator protein and reactive oxygen species in apoptosis of THP-1 macrophages induced by sonodynamic therapy.
P2860
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P2860
PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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name
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@en
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@nl
type
label
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@en
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@nl
prefLabel
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@en
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@nl
P2093
P2860
P50
P356
P1433
P1476
PK11195 potently sensitizes to ...... pheral benzodiazepin receptor.
@en
P2093
Claire Fabre
Didier Decaudin
Gabrielle Carvalho
Ibtissam Youlyouz-Marfak
Martine Raphael
Patrice Codogno
Rosa-Ana Gonzalez-Polo
Thorsten Braun
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208907
P407
P577
2005-11-01T00:00:00Z