A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.
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Persistent Associations between Maternal Prenatal Exposure to Phthalates on Child IQ at Age 7 YearsPlastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutationsCumulative effects of in utero administration of mixtures of reproductive toxicants that disrupt common target tissues via diverse mechanisms of toxicityPrenatal phthalate exposure and reduced masculine play in boysEnvironmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humansXenotransplantation models to study the effects of toxicants on human fetal tissuesSex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicalsMechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalateAn Informatics Approach to Reading the Label: Identifying Common Chemical Mixtures in Personal Care ProductsMechanisms mediating environmental chemical-induced endocrine disruption in the adrenal glandEnvironmental/lifestyle effects on spermatogenesisMaternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of ageSelf-reported chemicals exposure, beliefs about disease causation, and risk of breast cancer in the Cape Cod Breast Cancer and Environment Study: a case-control studyChanges in Cosmetics Use during Pregnancy and Risk Perception by WomenEarly Life Exposure to Endocrine Disrupting Chemicals and Childhood Obesity and NeurodevelopmentDifferential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay.Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP).Cognitive deficits and anxiety induced by diisononyl phthalate in mice and the neuroprotective effects of melatonin.Associations between bone mineral density and urinary phthalate metabolites among post-menopausal women: a cross-sectional study of NHANES data 2005-2010.Synergistic disruption of external male sex organ development by a mixture of four antiandrogens.Gestational exposure to endocrine-disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4- and 5-year-old children: the HOME study.Personal care product use and urinary phthalate metabolite and paraben concentrations during pregnancy among women from a fertility clinic.Co-treatment of mouse antral follicles with 17β-estradiol interferes with mono-2-ethylhexyl phthalate (MEHP)-induced atresia and altered apoptosis gene expression.Racial/ethnic disparities in environmental endocrine disrupting chemicals and women's reproductive health outcomes: epidemiological examples across the life courseTargeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals.Components of plastic: experimental studies in animals and relevance for human health.Prenatal and peripubertal phthalates and bisphenol A in relation to sex hormones and puberty in boysLinking empirical estimates of body burden of environmental chemicals and wellness using NHANES data.Personal care products and endocrine disruption: A critical review of the literature.In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats.Endocrine disruptors and asthma-associated chemicals in consumer productsToxicogenomic Screening of Replacements for Di(2-Ethylhexyl) Phthalate (DEHP) Using the Immortalized TM4 Sertoli Cell LineDipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.Children's phthalate intakes and resultant cumulative exposures estimated from urine compared with estimates from dust ingestion, inhalation and dermal absorption in their homes and daycare centers.In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat.Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetusMaternal and fetal tissue accumulation of selected endocrine disrupting compounds (EDCs) following exposure to sewage sludge-treated pastures before or after conceptionEffects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.Daily exposure to Di(2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice.A short-term in vivo screen using fetal testosterone production, a key event in the phthalate adverse outcome pathway, to predict disruption of sexual differentiation
P2860
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P2860
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
A mixture of five phthalate es ...... ulative, dose-additive manner.
@en
A mixture of five phthalate es ...... ulative, dose-additive manner.
@nl
type
label
A mixture of five phthalate es ...... ulative, dose-additive manner.
@en
A mixture of five phthalate es ...... ulative, dose-additive manner.
@nl
prefLabel
A mixture of five phthalate es ...... ulative, dose-additive manner.
@en
A mixture of five phthalate es ...... ulative, dose-additive manner.
@nl
P2093
P2860
P356
P1476
A mixture of five phthalate es ...... ulative, dose-additive manner.
@en
P2093
Andrew K Hotchkiss
Chad R Blystone
Christy R Lambright
Cynthia V Rider
Johnathan Furr
Kembra L Howdeshell
Leon Earl Gray
P2860
P304
P356
10.1093/TOXSCI/KFN077
P577
2008-04-14T00:00:00Z