Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. - Wikidata - awgldk - TriplyDB

Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.

Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.

http://www.wikidata.org/entity/Q46662642

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Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction Reduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibition ACE2 activation promotes antithrombotic activity.Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases.Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension.Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes.From gene to protein-experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension Prediction of off-target effects on angiotensin-converting enzyme 2.Angiotensin II-related hypertension and eye diseases.Renin-angiotensin system in the kidney: What is new?Angiotensin-converting enzymes and drug discovery in cardiovascular diseases.Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats.ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases.ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injury Targeting the ACE2-Ang-(1-7) pathway in cardiac fibroblasts to treat cardiac remodeling and heart failure Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2.ACE and ACE2 in kidney disease Short-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy.Role of non-classical renin-angiotensin system axis in renal fibrosis.Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.Angiotensin-converting enzyme 2: the first decade.ACE2 and Microbiota: Emerging Targets for Cardiopulmonary Disease Therapy Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats.Expression of MAS1 in breast cancer.ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis.Changes in Angiotensin Receptor Distribution and in Aortic Morphology Are Associated with Blood Pressure Control in Aged Metabolic Syndrome Rats Angiotensin-converting enzyme 2 activation improves endothelial function Angiotensin-converting enzyme 2 in the brain: properties and future directions.Association of exercise training and angiotensin-converting enzyme 2 activator improves baroreflex sensitivity of spontaneously hypertensive rats Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.New agents modulating the renin-angiotensin-aldosterone system-Will there be a new therapeutic option?Downregulation of Renal G Protein-Coupled Receptor Kinase Type 4 Expression via Ultrasound-Targeted Microbubble Destruction Lowers Blood Pressure in Spontaneously Hypertensive Rats.Angiotensin-converting enzyme 2 as a therapeutic target for heart failure Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension.New pathways of the renin-angiotensin system: the role of ACE2 in cardiovascular pathophysiology and therapy.Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro

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P2860

Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.

http://www.wikidata.org/entity/Q46662642

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Structure-based identification ...... novel antihypertensive agents.

@en

Structure-based identification ...... novel antihypertensive agents.

@nl

type

label

Structure-based identification ...... novel antihypertensive agents.

@en

Structure-based identification ...... novel antihypertensive agents.

@nl

prefLabel

Structure-based identification ...... novel antihypertensive agents.

@en

Structure-based identification ...... novel antihypertensive agents.

@nl

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Structure-based identification ...... novel antihypertensive agents

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Anderson J Ferreira

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Andrew J Lampkins

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David A Ostrov

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José A Hernández Prada

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Michael J Katovich

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Mohan K Raizada

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Ronald K Castellano

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Vinayak Shenoy

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Yanfei Qi

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1312-1317

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scholarly article

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10.1161/HYPERTENSIONAHA.107.108944

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5

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51

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Vladimir Gubala

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2008-04-07T00:00:00Z

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18391097

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