The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
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Identification of a nonneuronal isoform of synaptotagminDoc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter releaseGenetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter releaseCa2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin IComplexins: small but capableDisruption of axonal transport perturbs bone morphogenetic protein (BMP)--signaling and contributes to synaptic abnormalities in two neurodegenerative diseasesAP180 maintains the distribution of synaptic and vesicle proteins in the nerve terminal and indirectly regulates the efficacy of Ca2+-triggered exocytosisSynaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brainIdentification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cellsDelineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagminRat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusionThe AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosisThe C2H2 zinc-finger protein SYD-9 is a putative posttranscriptional regulator for synaptic transmissionAxonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screenAutapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I.Evoked and spontaneous transmission favored by distinct sets of synapses.Genetic evidence for an equilibrium between docked and undocked vesicles.Evidence for synaptotagmin as an inhibitory clamp on synaptic vesicle release in Aplysia neuronsThe first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic beta-cells: action of synaptotagmin at low micromolar calcium.Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis.Synaptotagmin I is a molecular target for lead.Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1.Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivoMolecular mechanisms of neurotransmitter release.Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.Ca2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1Post-transcriptional silencing and functional characterization of the Drosophila melanogaster homolog of human Surf1.A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.Role of synaptotagmin in Ca2+-triggered exocytosis.Visualization of synaptotagmin I oligomers assembled onto lipid monolayers.Lysosomes and the plasma membrane: trypanosomes reveal a secret relationshipMembrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo.NLP-12 engages different UNC-13 proteins to potentiate tonic and evoked release.Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion.Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission.Differential expression and function of synaptotagmin 1 isoforms in Caenorhabditis elegansCalcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
P2860
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P2860
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@en
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@nl
type
label
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@en
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@nl
prefLabel
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@en
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@nl
P1433
P1476
The effect on synaptic physiology of synaptotagmin mutations in Drosophila.
@en
P2093
DiAntonio A
Schwarz TL
P304
P356
10.1016/0896-6273(94)90342-5
P407
P577
1994-04-01T00:00:00Z