Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
about
Different subcellular localization of Saccharomyces cerevisiae HMG-CoA reductase isozymes at elevated levels corresponds to distinct endoplasmic reticulum membrane proliferations.Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndromeDifferential regulation of multiple gap junction transcripts and proteins during rat liver regeneration.Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells.Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast.Oocyte activation and passage through the metaphase/anaphase transition of the meiotic cell cycle is blocked in clams by inhibitors of HMG-CoA reductase activity.Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase.Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells.Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase.Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cellsMetabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.Dermatomyositis and Immune-Mediated Necrotizing Myopathies: A Window on Autoimmunity and Cancer.Proteostatic Tactics in the Strategy of Sterol Regulation.Mallostery: Filling a niche between quality and metabolic control
P2860
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P2860
Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@en
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@nl
type
label
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@en
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@nl
prefLabel
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@en
Distinct sterol and nonsterol ...... -methylglutaryl-CoA reductase.
@nl
P1476
Distinct sterol and nonsterol ...... 3-methylglutaryl-CoA reductase
@en
P2093
J Roitelman
R D Simoni
P304
25264-25273
P407
P577
1992-12-01T00:00:00Z