Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. - Wikidata - awgldk - TriplyDB

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

http://www.wikidata.org/entity/Q46681141

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Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri Vinculin binding in its closed conformation by a helix addition mechanism Talin Dependent Mechanosensitivity of Cell Focal Adhesions The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin Vinculin controls talin engagement with the actomyosin machinery.The structure of the C-terminal actin-binding domain of talin Structural Determinants of Integrin Binding to the Talin Rod The Structure of an Interdomain Complex That Regulates Talin Activity The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin Novel Vinculin Binding Site of the IpaA Invasin of Shigella The Rickettsia Surface Cell Antigen 4 Applies Mimicry to Bind to and Activate Vinculin RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin Molecular dynamics study of talin-vinculin binding.Vinculin is a dually regulated actin filament barbed end-capping and side-binding protein Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring.How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism.Nanoscale architecture of cadherin-based cell adhesions.Talins and kindlins: partners in integrin-mediated adhesion.A molecular dynamics investigation of vinculin activation.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.Identification of Hic-5 as a novel regulatory factor for integrin αIIbβ3 activation and platelet aggregation in mice.The talin dimer structure orientation is mechanically regulated.Molecular mechanisms of host cytoskeletal rearrangements by Shigella invasins.Vinculin activation is necessary for complete talin binding Integrin-mediated internalization of Staphylococcus aureus does not require vinculin The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms The desmin coil 1B mutation K190A impairs nebulin Z-disc assembly and destabilizes actin thin filaments.New insights into vinculin function and regulation.A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.Subcellular localization of talin is regulated by inter-domain interactions αE-catenin is an autoinhibited molecule that coactivates vinculin.

P2860

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P2860

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

http://www.wikidata.org/entity/Q46681141

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

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2005年學術文章

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2005年學術文章

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name

Mapping and consensus sequence ...... ng sites within the talin rod.

@en

Mapping and consensus sequence ...... ng sites within the talin rod.

@nl

type

label

Mapping and consensus sequence ...... ng sites within the talin rod.

@en

Mapping and consensus sequence ...... ng sites within the talin rod.

@nl

prefLabel

Mapping and consensus sequence ...... ng sites within the talin rod.

@en

Mapping and consensus sequence ...... ng sites within the talin rod.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Mapping and consensus sequence ...... ng sites within the talin rod.

@en

P2093

David R Critchley

http://www.w3.org/2001/XMLSchema#string

Igor L Barsukov

http://www.w3.org/2001/XMLSchema#string

Jonas Emsley

http://www.w3.org/2001/XMLSchema#string

Ronald Frank

http://www.w3.org/2001/XMLSchema#string

P2860

Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

F-actin binding site masked by the intramolecular association of vinculin head and tail domains

The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

SWISS-MODEL: An automated protein homology-modeling server

The structural basis of localization and signaling by the focal adhesion targeting domain

Vinculin activation by talin through helical bundle conversion

Protein secondary structure prediction based on position-specific scoring matrices

P304

37217-37224

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scholarly article

P356

10.1074/JBC.M508060200

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P433

44

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P478

280

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P50

Alexandre R Gingras

Wolfgang H. Ziegler

P577

2005-08-30T00:00:00Z

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P698

16135522

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