Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.
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Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese menGestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscleFat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance?Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function.Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects.Mitochondrial metabolism and diabetesProtein and energy metabolism in type 1 diabetes.The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance.Obesity in the elderly: is faulty metabolism to blame?Mitochondrial complex I deficiency enhances skeletal myogenesis but impairs insulin signaling through SIRT1 inactivation.Skeletal muscle phosphodiester content relates to body mass and glycemic control.Effects of exercise training on mitochondrial function in patients with type 2 diabetes.Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity.Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans.Mechanisms of insulin resistance in obesityLimited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men.Tissue-specific effects of bariatric surgery including mitochondrial functionRegulation of skeletal muscle mitochondrial function: genes to proteins.Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistanceSkeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetesAssessment of in vivo mitochondrial metabolism by magnetic resonance spectroscopy.Characteristics of glucose metabolism in Nordic and South Asian subjects with type 2 diabetes.Standard magnetic resonance-based measurements of the Pi→ATP rate do not index the rate of oxidative phosphorylation in cardiac and skeletal muscles.Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training.A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humansThe need for co-ordinated studies for obesity-related problems like diabetes mellitus in Libyan population.Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial FunctionThe critical role of metabolic pathways in aging.The role of mitochondria in the pathogenesis of type 2 diabetesAdiposity and immune-muscle crosstalk in South Asians &Europeans: A cross-sectional study.Nine days of intensive exercise training improves mitochondrial function but not insulin action in adult offspring of mothers with type 2 diabetes.Secondary muscle pathology and metabolic dysregulation in adults with cerebral palsyEffect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistanceThe Ups and Downs of Insulin Resistance and Type 2 Diabetes: Lessons from Genomic Analyses in HumansIntegration of cellular bioenergetics with mitochondrial quality control and autophagy.Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction."Deficiency" of mitochondria in muscle does not cause insulin resistance.Insulin sensitivity: modulation by nutrients and inflammation.Mitochondrial inhibitor as a new class of insulin sensitizer.
P2860
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P2860
Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@en
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@nl
type
label
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@en
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@nl
prefLabel
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@en
Asian Indians have enhanced sk ...... ith severe insulin resistance.
@nl
P2093
P356
P1433
P1476
Asian Indians have enhanced sk ...... with severe insulin resistance
@en
P2093
Jill M Coenen-Schimke
K Sreekumaran Nair
Katherine A Klaus
Maureen L Bigelow
Raghavakaimal Sreekumar
Yan W Asmann
Zeng-Kui Guo
P304
P356
10.2337/DB07-1556
P407
P577
2008-02-19T00:00:00Z