I2-Catalyzed enantioselective ring expansion of beta-lactams to gamma-lactams through a novel C3-C4 bond cleavage. Direct entry to protected 3,4-dihydroxypyrrolidin-2-one derivatives.

I2-Catalyzed enantioselective ring expansion of beta-lactams to gamma-lactams through a novel C3-C4 bond cleavage. Direct entry to protected 3,4-dihydroxypyrrolidin-2-one derivatives.