A mutation in the cone-specific pde6 gene causes rapid cone photoreceptor degeneration in zebrafish.
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A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal DegenerationGenomic evidence for rod monochromacy in sloths and armadillos suggests early subterranean history for XenarthraPhosphodiesterase 6C, cGMP-specific cone alpha'.Loss of Pde6 reduces cell body Ca(2+) transients within photoreceptorsGenetic dissection reveals two separate pathways for rod and cone regeneration in the teleost retinaZebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formationWild-type cone photoreceptors persist despite neighboring mutant cone degeneration.Knockdown of a zebrafish aryl hydrocarbon receptor repressor (AHRRa) affects expression of genes related to photoreceptor development and hematopoiesisThe Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cellsUtilizing Zebrafish Visual Behaviors in Drug Screening for Retinal DegenerationCelsr3 is required for normal development of GABA circuits in the inner retina.Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.Genetics of photoreceptor degeneration and regeneration in zebrafish.Deep mRNA sequencing analysis to capture the transcriptome landscape of zebrafish embryos and larvae.Differential role for synaptojanin 1 in rod and cone photoreceptors.Zebrafish guanylate cyclase type 3 signaling in cone photoreceptors.Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber.Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration.Purification of cone outer segment for proteomic analysis on its membrane proteins in carp retina.Arf6 and the 5'phosphatase of Synaptojanin 1 regulate autophagy in cone photoreceptorsRod photoreceptors protect from cone degeneration-induced retinal remodeling and restore visual responses in zebrafish.Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene.Gene therapy approaches for the treatment of retinal disordersAipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish.Investigating the genetics of visual processing, function and behaviour in zebrafish.The genetics of ocular disorders: insights from the zebrafish.Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?Functional architecture of the retina: development and disease.A Rare Form of Retinal Dystrophy Caused by Hypomorphic Nonsense Mutations in CEP290.Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafishA review of the mechanisms of cone degeneration in retinitis pigmentosa.Retinal Degeneration and Regeneration-Lessons From Fishes and Amphibians.Metabolic and redox signaling in the retina.A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model.The loss and recovery of vertebrate vision examined in microplates.Mitochondria Maintain Distinct Ca2+ Pools in Cone Photoreceptors.Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa.Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish.
P2860
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P2860
A mutation in the cone-specific pde6 gene causes rapid cone photoreceptor degeneration in zebrafish.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@en
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@nl
type
label
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@en
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@nl
prefLabel
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@en
A mutation in the cone-specifi ...... tor degeneration in zebrafish.
@nl
P2093
P1476
A mutation in the cone-specifi ...... ptor degeneration in zebrafish
@en
P2093
George Stearns
James M Fadool
Meradelfa Evangelista
Susan E Brockerhoff
P304
13866-13874
P356
10.1523/JNEUROSCI.3136-07.2007
P407
P577
2007-12-01T00:00:00Z