Cdc42 regulates cofilin during the establishment of neuronal polarity.
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Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.Swf1p, a member of the DHHC-CRD family of palmitoyltransferases, regulates the actin cytoskeleton and polarized secretion independently of its DHHC motifFunctional impact of splice isoform diversity in individual cellsRegulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in DiseaseExtracellular and Intracellular Signaling for Neuronal PolarityThe DLK signalling pathway--a double-edged sword in neural development and regenerationReconstitution of actin-based motility by vasodilator-stimulated phosphoprotein (VASP) depends on the recruitment of F-actin seeds from the solution produced by cofilin.Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice.The DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathwaysCdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathwayNon-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cellsNeuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2Cytoskeletal pathologies of Alzheimer diseaseGrowth cone-like waves transport actin and promote axonogenesis and neurite branching.Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1.Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum.Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex.Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cuesSmall molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods.A second-site noncomplementation screen for modifiers of Rho1 signaling during imaginal disc morphogenesis in Drosophila.Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario.Neuronal Polarity in the Embryonic Mammalian Cerebral Cortex.The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channelLoss of Cdc42 leads to defects in synaptic plasticity and remote memory recall.Cellular responses to extracellular guidance cuesLuteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin.MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activityPtdIns (3,4,5) P3 recruitment of Myo10 is essential for axon developmentSignaling role of Cdc42 in regulating mammalian physiology.Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylationThe growth cone cytoskeleton in axon outgrowth and guidance.Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies.A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neuronsNuclear transport of the serum response factor coactivator MRTF-A is downregulated at tensional homeostasis.Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons.Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?Neuronal polarization in the developing cerebral cortex.Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors
P2860
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P2860
Cdc42 regulates cofilin during the establishment of neuronal polarity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@en
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@nl
type
label
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@en
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@nl
prefLabel
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@en
Cdc42 regulates cofilin during the establishment of neuronal polarity.
@nl
P2093
P50
P1476
Cdc42 regulates cofilin during the establishment of neuronal polarity
@en
P2093
Dorothee Neukirchen
Frank Bradke
James R Bamburg
Kevin C Flynn
Liane Meyn
P304
13117-13129
P356
10.1523/JNEUROSCI.3322-07.2007
P407
P577
2007-11-01T00:00:00Z