Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment. - Wikidata - awgldk - TriplyDB

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.

http://www.wikidata.org/entity/Q46891204

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Molecular mechanisms of biological aging in intervertebral discs Diversity of intervertebral disc cells: phenotype and function Mechanical design criteria for intervertebral disc tissue engineering Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc Nucleus pulposus tissue engineering: a brief review Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to LDD in Chinese cohort Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus.FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc di Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.Expression of acid-sensing ion channels in nucleus pulposus cells of the human intervertebral disk is regulated by non-steroid anti-inflammatory drugs.HIF-1α polymorphism in the susceptibility of cervical spondylotic myelopathy and its outcome after anterior cervical corpectomy and fusion treatment.PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells.Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs.Effects of hypoxias and scaffold architecture on rabbit mesenchymal stem cell differentiation towards a nucleus pulposus-like phenotype.Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc.Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting Hypoxic regulation of functional extracellular matrix elaboration by nucleus pulposus cells in long-term agarose culture Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degeneration HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells.3D finite element analysis of nutrient distributions and cell viability in the intervertebral disc: effects of deformation and degeneration.FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc Responses of human adipose-derived mesenchymal stem cells to chemical microenvironment of the intervertebral disc.Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.Regulatory role of hypoxia inducible factor in the biological behavior of nucleus pulposus cells Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.

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Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.

http://www.wikidata.org/entity/Q46891204

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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name

Nucleus pulposus cells express ...... rtebral disc microenvironment.

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Nucleus pulposus cells express ...... rtebral disc microenvironment.

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type

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Nucleus pulposus cells express ...... rtebral disc microenvironment.

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Nucleus pulposus cells express ...... rtebral disc microenvironment.

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Nucleus pulposus cells express ...... rtebral disc microenvironment.

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Nucleus pulposus cells express ...... rtebral disc microenvironment.

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Asha Guttapalli

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David G Stokes

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David Hawkins

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Irving M Shapiro

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Keith G Danielson

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Makarand V Risbud

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Thomas P Schaer

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Todd J Albert

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152-159

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10.1002/JCB.20765

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1

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98

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2006-05-01T00:00:00Z

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16408279

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metabolic adaptation