Deletion of copies of the gene encoding old yellow enzyme (TcOYE), a NAD(P)H flavin oxidoreductase, associates with in vitro-induced benznidazole resistance in Trypanosoma cruzi.
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Bioactive lipids in Trypanosoma cruzi infectionToxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)Benznidazole biotransformation and multiple targets in Trypanosoma cruzi revealed by metabolomicsDrug resistance in eukaryotic microorganisms.Functional analysis of cytosolic tryparedoxin peroxidase in antimony-resistant and -susceptible Leishmania braziliensis and Leishmania infantum lines.Intraspecies variation in Trypanosoma cruzi GPI-mucins: biological activities and differential expression of α-galactosyl residues.Molecular characterization of the hexose transporter gene in benznidazole resistant and susceptible populations of Trypanosoma cruzi.A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes.Putative Role of the Aldo-Keto Reductase from Trypanosoma cruzi in Benznidazole Metabolism.Proteomic analysis of detergent-solubilized membrane proteins from insect-developmental forms of Trypanosoma cruzi.Trypanocidal drugs: mechanisms, resistance and new targets.Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benzonidazole in Trypanosoma cruziTranscriptome and Functional Genomics Reveal the Participation of Adenine Phosphoribosyltransferase in Trypanosoma cruzi Resistance to Benznidazole.P-glycoprotein efflux pump plays an important role in Trypanosoma cruzi drug resistance.Structural insights into stereospecific reduction of α, β-unsaturated carbonyl substrates by old yellow enzyme from Gluconobacter oxydans.Trypanosoma cruzi alkaline 2-DE: Optimization and application to comparative proteome analysis of flagellate life stages.Experimental and Clinical Treatment of Chagas Disease: A Review.Microsatellite and mini-exon analysis of Mexican human DTU I Trypanosoma cruzi strains and their susceptibility to nifurtimox and benznidazole.Prostaglandin F2α synthase in Trypanosoma cruzi plays critical roles in oxidative stress and susceptibility to benznidazole.Use of clomipramine as chemotherapy of the chronic phase of Chagas disease.The level of ascorbate peroxidase is enhanced in benznidazole-resistant populations of Trypanosoma cruzi and its expression is modulated by stress generated by hydrogen peroxide.Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.Endogenous overexpression of an active phosphorylated form of DNA polymerase β under oxidative stress in Trypanosoma cruzi.Quantitative proteomics of Trypanosoma cruzi during metacyclogenesis.Old Yellow Enzyme from Trypanosoma cruzi Exhibits In Vivo Prostaglandin F2α Synthase Activity and Has a Key Role in Parasite Infection and Drug Susceptibility.The crystal structure of XdpB, the bacterial old yellow enzyme, in an FMN-free form.A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
P2860
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P2860
Deletion of copies of the gene encoding old yellow enzyme (TcOYE), a NAD(P)H flavin oxidoreductase, associates with in vitro-induced benznidazole resistance in Trypanosoma cruzi.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@en
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@nl
type
label
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@en
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@nl
prefLabel
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@en
Deletion of copies of the gene ...... sistance in Trypanosoma cruzi.
@nl
P2093
P1476
Deletion of copies of the gene ...... esistance in Trypanosoma cruzi
@en
P2093
Alvaro J Romanha
Andréa R Avila
Christian M Probst
Fernanda F M Campos
Luciana R Montenegro
Marco A Krieger
Nair H Muto
Philippe Nirdé
Regina C de Oliveira
Samuel Goldenberg
P304
P356
10.1016/J.MOLBIOPARA.2005.12.001
P577
2005-12-27T00:00:00Z