MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.
about
Identification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-largeMEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment.Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.ERK and JNK activation is essential for oncogenic transformation by v-Rel.Neurotrophic and neuroprotective actions of (-)- and (+)-phenserine, candidate drugs for Alzheimer's disease.ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytesERK2 is essential for the growth of human epithelioid malignant mesotheliomas.An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury.Mitogen-activated Protein Kinase Kinase 2 (MEK2), a Novel E2-interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway.c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial-mesenchymal transition and invasion in prostate cancerThe MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control.Nuclear translocation of MEK1 triggers a complex T cell response through the corepressor silencing mediator of retinoid and thyroid hormone receptor.On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry.ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.Biphasic activation of extracellular signal-regulated kinase (ERK) 1/2 in epidermal growth factor (EGF)-stimulated SW480 colorectal cancer cells.Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis.Novel mitogen-activated protein kinase kinase inhibitors.MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells.Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase.Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway.BPGAP1 spatially integrates JNK/ERK signaling crosstalk in oncogenesis.FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes.A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes.
P2860
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P2860
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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name
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@en
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@nl
type
label
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@en
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@nl
prefLabel
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@en
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@nl
P2093
P356
P1433
P1476
MEK1 and MEK2 regulate distinc ...... nt intracellular compartments.
@en
P2093
Bjørn Steen Skålhegg
Carola Maria Rosseland
Ellen Skarpen
Henrik Sverre Huitfeldt
Lene Wierød
Liv Ingrid Flinder
Morten Pedersen Oksvold
Sigurd Orstavik
P304
P356
10.1096/FJ.07-8650COM
P407
P577
2007-10-10T00:00:00Z