about
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cellsAlpha-Ketoglutarate: Physiological Functions and ApplicationsRapalogs in cancer prevention: anti-aging or anticancer?Organization of the ENaC-regulatory machineryMtl1 is required to activate general stress response through Tor1 and Ras2 inhibition under conditions of glucose starvation and oxidative stressE3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodelingA Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin actionBig mice die young but large animals live longerTarget Of Rapamycin (TOR) SignalingRapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity.Evaluation of everolimus in renal cell cancer.RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients.Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinaseCrosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancerWith TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in agingLongitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic miceMammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.In silico discovery of novel transcription factors regulated by mTOR-pathway activities.Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in miceMetformin and sex: Why suppression of aging may be harmful to young male mice.Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expressionPI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation.Role of TOR signaling in aging and related biological processes in Drosophila melanogasterBnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.Targeting the Akt/mTOR pathway in Brca1-deficient cancers.Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophages.The tuberous sclerosis complex-mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells.mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.GLUT1 enhances mTOR activity independently of TSC2 and AMPK.Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.LKB1 regulates development and the stress response in DictyosteliumPoint mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cellsNCI's provocative questions on cancer: some answers to ignite discussion.Clinical experience with temsirolimus in the treatment of advanced renal cell carcinomaRapamycin Attenuates Splenomegaly in both Intrahepatic and Prehepatic Portal Hypertensive Rats by Blocking mTOR Signaling Pathway.The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulationKrüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Complexity of the TOR signaling network.
@en
Complexity of the TOR signaling network.
@nl
type
label
Complexity of the TOR signaling network.
@en
Complexity of the TOR signaling network.
@nl
prefLabel
Complexity of the TOR signaling network.
@en
Complexity of the TOR signaling network.
@nl
P1476
Complexity of the TOR signaling network.
@en
P2093
Kun-Liang Guan
P304
P356
10.1016/J.TCB.2006.02.002
P577
2006-03-03T00:00:00Z