The Rab8 GTPase regulates apical protein localization in intestinal cells.
about
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteinsFamily-wide characterization of the DENN domain Rab GDP-GTP exchange factorsOverexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in miceMICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8aRole of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarityThe role of enterocyte defects in the pathogenesis of congenital diarrheal disordersSmall GTPase regulation of GPCR anterograde traffickingPolar delivery in plants; commonalities and differences to animal epithelial cellsThe bigger the better: determining nephron size in kidneyDisruption of the C. elegans Intestinal Brush Border by the Fungal Lectin CCL2 Phenocopies Dietary Lectin Toxicity in MammalsBasolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to EndosomesHuntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKCTrafficking of Sendai virus nucleocapsids is mediated by intracellular vesiclesCLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic traffickingNon-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cellsgammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogasterSyntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segmentsGeneration of intestinal surface: an absorbing taleMyosin Vc is a molecular motor that functions in secretory granule traffickingInteraction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degenerationRhoA regulates peroxisome association to microtubules and the actin cytoskeletonTransport, metabolism, and endosomal trafficking-dependent regulation of intestinal fructose absorptionClathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neuronsRab14 regulates apical targeting in polarized epithelial cells.p31 deficiency influences endoplasmic reticulum tubular morphology and cell survivalAhi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle traffickingCdx2 regulates endo-lysosomal function and epithelial cell polarityLoss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in miceCrystal structure of the Rab binding domain of OCRL1 in complex with Rab8 and functional implications of the OCRL1/Rab8 module for Lowe syndromeCaveolin-1 induces formation of membrane tubules that sense actomyosin tension and are inhibited by polymerase I and transcript release factor/cavin-1.Trafficking of Crumbs3 during cytokinesis is crucial for lumen formation.Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease.The small GTPase RAB-11 directs polarized exocytosis of the intracellular pathogen N. parisii for fecal-oral transmission from C. elegansThe Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells.Rab8 interacts with distinct motifs in alpha2B- and beta2-adrenergic receptors and differentially modulates their transport.EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegansFrom cells to organs: building polarized tissue.Polarized sorting and trafficking in epithelial cellsTLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis.Global ablation of the mouse Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion.
P2860
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P2860
The Rab8 GTPase regulates apical protein localization in intestinal cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@en
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@nl
type
label
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@en
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@nl
prefLabel
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@en
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@nl
P2093
P356
P1433
P1476
The Rab8 GTPase regulates apical protein localization in intestinal cells.
@en
P2093
Akihiro Harada
Akira Tsuji
Kazunori Miki
Keiichi Ozono
Miyuki Sato
Naoki Takeda
Reiko Harada
Sotaro Mushiake
Takashi Sato
P2888
P304
P356
10.1038/NATURE05929
P407
P577
2007-06-27T00:00:00Z
P6179
1021151865