Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin.
about
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complexWnt/beta-catenin signaling: components, mechanisms, and diseasesTargeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingThe many faces and functions of β-cateninEvolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regenerationActivation of wingless targets requires bipartite recognition of DNA by TCFThe function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.Wingless signalling alters the levels, subcellular distribution and dynamics of Armadillo and E-cadherin in third instar larval wing imaginal discs.The regulation of β-catenin activity and function in cancer: therapeutic opportunitiesDisturbed Wnt Signalling due to a Mutation in CCDC88C Causes an Autosomal Recessive Non-Syndromic Hydrocephalus with Medial Diverticulum.Crosstalk between microRNA30a/b/c/d/e-5p and the canonical Wnt pathway: implications for multiple myeloma therapyWingless/Wnt signaling in Drosophila: the pattern and the pathwayPygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.Probing transcription-specific outputs of β-catenin in vivo.Wnt/β-Catenin Signaling Pathway in Skin Carcinogenesis and Therapy.An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.Powerful Drosophila screens that paved the wingless pathway.Probing the canonicity of the Wnt/Wingless signaling pathway.The role of Wnt signaling in cancer and stem cells.BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.Wnt signaling in ovarian tumorigenesisPhospho-regulation of Beta-catenin adhesion and signaling functions.The miR-310/13 cluster antagonizes β-catenin function in the regulation of germ and somatic cell differentiation in the Drosophila testis.A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcriptionCardiac gene regulatory networks in Drosophila.The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway.Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer.Vertebrate Axial Patterning: From Egg to Asymmetry.Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin.The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.CBP/p300 are bimodal regulators of Wnt signaling.The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.C-terminal-binding protein directly activates and represses Wnt transcriptional targets in DrosophilaUnderstanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia.
P2860
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P2860
Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@en
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@nl
type
label
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@en
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@nl
prefLabel
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@en
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@nl
P2093
P1433
P1476
Pygopus and legless provide es ...... ons to armadillo/beta-catenin.
@en
P2093
Konrad Basler
Raymond Hoffmans
Reto Städeli
P304
P356
10.1016/J.CUB.2005.05.054
P407
P577
2005-07-01T00:00:00Z