AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.
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Angiomotin Family Members: Oncogenes or Tumor Suppressors?Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish.AmotL2 integrates polarity and junctional cues to modulate cell shape.Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.Cell-cell junctional mechanotransduction in endothelial remodeling.The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching.Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis.AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.Small Rho GTPase-mediated actin dynamics at endothelial adherens junctions.Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism.Hippo-YAP/TAZ Signaling in Angiogenesis.The physiological role of Motin family and its dysregulation in tumorigenesis.
P2860
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P2860
AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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2014年學術文章
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name
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@en
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@nl
type
label
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@en
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@nl
prefLabel
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@en
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@nl
P2093
P2860
P50
P356
P1476
AmotL2 links VE-cadherin to co ...... ry for aortic lumen expansion.
@en
P2093
Arindam Majumdar
Christian Gentili
Christian S M Helker
Lars Holmgren
Mahdi Mojallal
Rachel Milloud
Sara Hultin
Simona Vertuani
Yujuan Zheng
P2860
P2888
P356
10.1038/NCOMMS4743
P407
P577
2014-05-07T00:00:00Z