Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
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A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner earPDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndromeVezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complexUsher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapyThe product of the split ends gene is required for the maintenance of positional information during Drosophila developmentHarmonin (Ush1c) is required in zebrafish Müller glial cells for photoreceptor synaptic development and functionChemical screening for hair cell loss and protection in the zebrafish lateral lineCharacterization of the motor activity of mammalian myosin VIIARole of myosin VIIa and Rab27a in the motility and localization of RPE melanosomesOtolith tethering in the zebrafish otic vesicle requires Otogelin and α-TectorinExcessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervationA convergent and essential interneuron pathway for Mauthner-cell-mediated escapes.Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein.Saccular Transcriptome Profiles of the Seasonal Breeding Plainfin Midshipman Fish (Porichthys notatus), a Teleost with Divergent Sexual Phenotypes.Sensory hair cell death and regeneration in fishesmyosin 7aa(-/-) mutant zebrafish show mild photoreceptor degeneration and reduced electroretinographic responses.The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A.Early development of hearing in zebrafishScreen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing.Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genesThe Usher gene cadherin 23 is expressed in the zebrafish brain and a subset of retinal amacrine cells.Neomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish (Danio rerio).Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic traumaDrug screening for hearing loss: using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss.Cell proliferation follows acoustically-induced hair cell bundle loss in the zebrafish saccule.Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereociliaZebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function.Cadherin-11 controls otolith assembly: evidence for extracellular cadherin activity.Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development.Myosin VI and VIIa distribution among inner ear epithelia in diverse fishes.Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila.Towards a molecular understanding of Drosophila hearingAnatomical and molecular design of the Drosophila antenna as a flagellar auditory organ.A subtracted cDNA library from the zebrafish (Danio rerio) embryonic inner ear.Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tension.Deafness mutation mining using regular expression based pattern matching.Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans.Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis.
P2860
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P2860
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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name
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@en
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@nl
type
label
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@en
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@nl
prefLabel
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@en
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@nl
P2093
P356
P1476
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
@en
P2093
P304
P356
10.1093/HMG/9.14.2189
P577
2000-09-01T00:00:00Z