FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.

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FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest.

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FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

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FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@nl

type

Item

label

FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@en

FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@nl

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FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@en

FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@nl

P1476

FGF21 mimetic antibody stimula ...... tho complex in non-adipocytes.

@en

P2093

Annie Ogasawara

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Ganesh Kolumam

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James Ziai

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Jose Zavala-Solorio

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Joshua C Chang

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Junichiro Sonoda

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Khanhky Phamluong

http://www.w3.org/2001/XMLSchema#string

Lance Kates

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Mark Z Chen

http://www.w3.org/2001/XMLSchema#string

Minh Thai

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P2860

Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target

Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

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1454-1467

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scholarly article

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10.1016/J.MOLMET.2017.09.003

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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Søren Warming

Victor Nunez

P577

2017-09-18T00:00:00Z

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P698

29107292

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5681280

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FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.

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P2860

P2860

FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.

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