JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B-Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B-Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation.

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P1476

JAK1/2 Inhibitors AZD1480 and ...... Disrupting Cell Proliferation

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A L F V Assumpção

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G Kong

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N Bollig

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P C Jark

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Z Lu

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Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

The Comparative Diagnostic Features of Canine and Human Lymphoma.

Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis.

Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.

Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

JAK inhibitors in myeloproliferative neoplasms: rationale, current data and perspective.

Authentication of primordial characteristics of the CLBL-1 cell line prove the integrity of a canine B-cell lymphoma in a murine in vivo model.

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1804-1815

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10.1111/JVIM.14837

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Courtney C Hong

X Pan

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2017-09-27T00:00:00Z

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28960447

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momelotinib

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