Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

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Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

@nl

P1476

Modeling the process of childhood ETV6-RUNX1 B-cell leukemias

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P2093

Ana Gavilán

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Arndt Borkhardt

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Daniel Schäfer

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Guillermo Rodríguez-Hernández

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Isidro Sánchez-García

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Julia Hauer

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P2860

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression

Low numbers of pre-leukemic fusion genes are frequently present in umbilical cord blood without affecting DNA damage response.

The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.

Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice.

TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia.

Origins of chromosome translocations in childhood leukaemia.

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

P304

102674-102680

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P31

scholarly article

review article

P356

10.18632/ONCOTARGET.21281

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English

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P478

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Carolina Vicente-Dueñas

P577

2017-09-27T00:00:00Z

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P698

29254279

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P932

5731989

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