CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis.

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Sepsis-Induced T Cell Immunoparalysis: The Ins and Outs of Impaired T Cell Immunity.

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CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis.

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P1476

CXCR4 blockade decreases CD4+ ...... model of polymicrobial sepsis

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Annette Hadley

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Ching-Wen Chen

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Craig M Coopersmith

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John D Lyons

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Katherine T Fay

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Kevin W McConnell

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Nathan J Klingensmith

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Wenxiao Zhang

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P2860

Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change?

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

AMD3100/CXCR4 Inhibitor

PD-1 and its ligands in tolerance and immunity

Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012

A randomized trial of protocol-based care for early septic shock

Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.

CXCR4 acts as a costimulator during thymic beta-selection.

Immunotherapy - a potential new way forward in the treatment of sepsis

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e0188882

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scholarly article

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10.1371/JOURNAL.PONE.0188882

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English

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Mandy L Ford

Kimberly M Ramonell

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2017-12-12T00:00:00Z

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29232699

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sepsis

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5726761

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CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis.

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P2860

P2860

CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis.

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P1433

P1476

P2093

P2860

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P356

P407

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P1433

P1476

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P2860

P304

P31

P356

P407

P433

P478

P50

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P921

P932