about
Protein flexibility is required for vesicle tethering at the Golgi.Rab6 regulation of the kinesin family KIF1C motor domain contributes to Golgi tethering.Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export.Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brainGenome-wide interrogation of extracellular vesicle biology using barcoded miRNAsLRRK2 and Rab GTPasesPPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteinsMembrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPasesNPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomesInter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteinsLRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Suzanne R Pfeffer
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Suzanne R Pfeffer
@en
Suzanne R Pfeffer
@es
Suzanne R Pfeffer
@nl
Suzanne R Pfeffer
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type
label
Suzanne R Pfeffer
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Suzanne R Pfeffer
@en
Suzanne R Pfeffer
@es
Suzanne R Pfeffer
@nl
Suzanne R Pfeffer
@sl
altLabel
Suzanne Pfeffer
@en
prefLabel
Suzanne R Pfeffer
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Suzanne R Pfeffer
@en
Suzanne R Pfeffer
@es
Suzanne R Pfeffer
@nl
Suzanne R Pfeffer
@sl
P106
P21
P2798
P31
P496
0000-0002-6462-984X