about
Structural basis for natural lactonase and promiscuous phosphotriesterase activitiesStructural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicusCharacterisation of the organophosphate hydrolase catalytic activity of SsoPoxCatalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPoxStructural and Enzymatic Characterization of the Phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenesAncestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding proteinCatalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzymeWhat makes a protein fold amenable to functional innovation? Fold polarity and stability trade-offsCrystal structure of the phosphate-binding protein (PBP-1) of an ABC-type phosphate transporter from Clostridium perfringensCrystallization and preliminary X-ray diffraction analysis of the lactonaseVmoLac fromVulcanisaeta moutnovskiaCrystallization, diffraction data collection and preliminary crystallographic analysis of DING protein from Pseudomonas fluorescens.Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1).Eukaryotic DING proteins are endogenous: an immunohistological study in mouse tissues.The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies.Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumoniaCrystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus islandicus lactonase.SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase.Stabilization of the active form(s) of human paraoxonase by human phosphate-binding protein.Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonasesThe DING family of phosphate binding proteins in inflammatory diseases.The quorum-quenching lactonase from Alicyclobacter acidoterrestris: purification, kinetic characterization, crystallization and crystallographic analysis.Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes.Phosphate-binding protein from Polaromonas JS666: purification, characterization, crystallization and sulfur SAD phasing.Biotechnological applications of quorum quenching enzymes.Crystallization and preliminary X-ray diffraction analysis of a DING protein from Pseudomonas aeruginosa PA14Evidence for phosphatase activity of p27SJ and its impact on the cell cycle.Structural insights and ab initio sequencing within the DING proteins family.Crystallization and preliminary X-ray diffraction analysis of the organophosphorus hydrolase OPHC2 from Pseudomonas pseudoalcaligenesCrystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia.Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus solfataricus phosphotriesterase.Crystallization and preliminary X-ray diffraction analysis of a high-affinity phosphate-binding protein endowed with phosphatase activity from Pseudomonas aeruginosa PAO1.Ambiguous evidence for assigning DddQ as a dimethylsulfoniopropionate lyase and oceanic dimethylsulfide producerNegative Epistasis and Evolvability in TEM-1 β-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder.The universality of enzymatic rate-temperature dependency.Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus.Elucidation of the phosphate binding mode of DING proteins revealed by subangstrom X-ray crystallography.Similar Active Sites and Mechanisms Do Not Lead to Cross-Promiscuity in Organophosphate Hydrolysis: Implications for Biotherapeutic Engineering.[DING proteins, their biochemical and structural properties, and their ability to inhibit HIV-1 replication].The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Mikael Elias
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Mikael Elias
@en
Mikael Elias
@es
Mikael Elias
@fr
Mikael Elias
@nl
Mikael Elias
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type
label
Mikael Elias
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Mikael Elias
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Mikael Elias
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Mikael Elias
@fr
Mikael Elias
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Mikael Elias
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prefLabel
Mikael Elias
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Mikael Elias
@en
Mikael Elias
@es
Mikael Elias
@fr
Mikael Elias
@nl
Mikael Elias
@sl
P106
P1153
34568561500
P21
P31
P496
0000-0003-0406-7539