The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease.

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The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

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The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

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Item

label

The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

@en

The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

@nl

prefLabel

The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

@en

The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

@nl

P1476

The prodrug of 7,8-dihydroxyfl ...... treating Alzheimer's disease.

@en

P2093

Chun Chen

http://www.w3.org/2001/XMLSchema#string

Keqiang Ye

http://www.w3.org/2001/XMLSchema#string

Seong Su Kang

http://www.w3.org/2001/XMLSchema#string

Xia Liu

http://www.w3.org/2001/XMLSchema#string

Ying Zhang

http://www.w3.org/2001/XMLSchema#string

Zhentao Zhang

http://www.w3.org/2001/XMLSchema#string

Zhihao Wang

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P2860

7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss

BDNF is essential to promote persistence of long-term memory storage

A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.

Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.

Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear.

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Brain-derived neurotrophic factor in neurodegenerative diseases.

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scholarly article

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10.1073/PNAS.1718683115

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English

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2018-01-02T00:00:00Z

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29295929

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Alzheimer's disease

7,8-Dihydroxyflavone

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5777001

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